The CTSF has available an High Content Screening (HCS) system for a variety of screenings and other large scale experiments. The HCS system includes incubation, robotics and liquid handling for screenings in living cell systems. In addition, the CTSF has two small molecule compound libraries that can be used in the HCS screening facility.
Temporal data storage is in collaboration with the CCBC.
Available software within the CTSF:
Harmony® High Content Imaging and Analysis Software provides a complete solution to set up assays and automate your high content imaging experiments, acquire images and analyze data, and then store, retrieve and present the results.
The PhenoLOGIC™ machine-learning option enables our High Content Analysis software to recognize different cell populations and regions using a simple learn-by-example approach. PhenoLOGIC sets parameters for optimal image segmentation and cell classification. The software combines the most meaningful parameters, whether it’s two, three, four or more, to achieve accurate classification of cells. The result is highly robust and statistically relevant results.
Columbus™ Scope system is a universal high-volume image data storage and analysis system that rings access to images from a wide range of sources including all major high content screening instruments via the Internet.
ImageJ/Fiji is a public domain Java image processing and analysis package. Customized image analysis can be performed in collaboration with Erasmus Optical Imaging Centre (OIC) and Biomedical Imaging Group Rotterdam (BIGR).
Download image analysis software: